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Drug dose reference

Adult dosing unless noted. Always verify against institutional protocol.

DrugDoseRoute / Notes
Albuterol MDI2 puffs (180 mcg)Inhaled
Repeat up to 3× as needed
Moderate allergic-like reaction
Atropine0.6–1.0 mgIV
May repeat. Max 3 mg total
Vasovagal reaction — severe
Atropine (peds)0.02 mg/kg (min 0.1 mg, max 0.6 mg)IV
For symptomatic bradycardia
Pediatric severe reaction — Epinephrine dosing
Diphenhydramine25–50 mgIV / IM / PO
Moderate allergic-like reaction
Diphenhydramine25–50 mgIV
Adjunct only
Severe allergic-like reaction / anaphylaxis
Diphenhydramine50 mgPO / IV / IM 1 h pre
Premedication — elective (13 h)
Diphenhydramine50 mg IVIV 1 h pre
Premedication — urgent (accelerated)
Diphenhydramine (Benadryl)25–50 mgPO / IV / IM
May cause drowsiness
Mild allergic-like reaction
Diphenhydramine (peds)1 mg/kg (max 50 mg)IV / IM
Pediatric severe reaction — Epinephrine dosing
Epinephrine (1 mg/mL)0.3 mL (0.3 mg) IM lateral thighIM
If progression to severe
Moderate allergic-like reaction
Epinephrine IM0.3 mg (0.3 mL of 1 mg/mL)IM lateral thigh
FIRST-LINE. Repeat q5–15 min
Severe allergic-like reaction / anaphylaxis
Epinephrine IM (peds)0.01 mg/kg (max 0.3 mg)IM lateral thigh
1 mg/mL concentration
Pediatric severe reaction — Epinephrine dosing
Epinephrine IV0.1 mg (1 mL of 0.1 mg/mL = 1:10,000)IV slow push 2–5 min
Only if hypotensive with IV access
Severe allergic-like reaction / anaphylaxis
Furosemide (Lasix)20–40 mgIV slow over 2 min
Pulmonary edema
Hydrocortisone200 mg IV q4 h until studyIV
Premedication — urgent (accelerated)
Labetalol20 mg IV (then 40, 80 mg q10 min, max 300 mg)IV slow push
Hypertensive crisis
Lorazepam2–4 mgIV slow
Seizure / convulsion
Methylprednisolone40 mgIV
Adjunct — onset 4–6 h
Severe allergic-like reaction / anaphylaxis
Methylprednisolone40 mg IV q4 h until studyIV
Premedication — urgent (accelerated)
Midazolam5 mgIM / Intranasal
Seizure / convulsion
Nitroglycerin0.4 mg SLSublingual
Repeat q5–10 min ×3
Hypertensive crisis
Normal Saline1 L wide openIV
Repeat as needed
Severe allergic-like reaction / anaphylaxis
Normal Saline (peds)20 mL/kg bolusIV
Pediatric severe reaction — Epinephrine dosing
Prednisone50 mg PO ×3 doses (13 h, 7 h, 1 h pre)PO
Premedication — elective (13 h)